Monthly Archives: June 2011

Michelle Gets a Boost from T3 (Cytomel)


Michelle shares her success story with T3. Michelle’s story demonstrates how combination therapy with T4 and T3 can be clinically superior to T4 (Synthroid, Levothyroxine) alone. In her story she mentions Wilson’s syndrome which I personally think is a “made up” diagnosis to help Dr. Wilson’s retirement fund but I do think her experience is fairly typical of a lot of people with hypothyroidism who eventually discover they need T3 added to conventional treatment with T4 to achieve best results.

Michelle writes:

OMG! Maybe I’m not crazy after all!
I’m 47 in December and can’t remember the last time I felt good or even okay. Same thing – doctors repeating same tests, thinking I’m exaggerating, sent to Psychiatrist…Over the past 6 years or so, major stress, low immune (sick all the time), worsening depression, borderline diabetes, high blood pressure, peri-menopause. Got to the point that I’m sooo exhausted. Don’t want to do anything. Lab diagnosis finally showed up hypothyroidism so doctor put me on Synthroid – I was so happy that I cried. Devastation set in after 6 months as this was not the miracle I thought it would be.

Started taking my temperature 3 to 4 x a day as suggested to me by a naturopath I had seen but couldn’t afford to keep going to. Again, measurements taken 3 x daily for a week averaged to 97.0. Talked to doctor about Wilson’s Temperature Syndrome; she did not believe in it and sent me for more blood tests which came back normal.

FINALLY (after 20 years at same doctor’s office) was lucky enough to be accepted under the care of a physician who hadn’t heard of WTS but had heard about the T4 not converting into the T3 (you all know the fault in the system)… so right then and there wrote me a prescription for Cytomel and told me to stop the synthroid. As the WTS website recommends sustained T3, I’m taking half the dose every 12 hours.

I started today and feel like a kid on Christmas Eve a million times over! I am so hopeful that this can get to the root of so many ailments. So many that I feel that I’m not even living my life, that I’m just here putting in everything I have just to get through the day.

With the lack of memory and concentration I have right now, I hope I remember to come back to this site and update you all!

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To Be Fair, New Diabetes Medications Have Some Use


In my last article on the newest generation of diabetes pills (the DPP-4 inhibitors), I basically said that their benefits were not impressive and the costs were too high. I stand by those comments, but I need to add some clarifying thoughts. I continue to use drugs like Januvia, Onglyza and Trajenta because certain individuals seem to get a better effect from them than I generally expect. If, for instance, a diabetic is on maximum dose of the older (and cheaper) diabetic medications and the glucose control is not good, instead of going directly to insulin as the next step, I will try the DPP-4 inhibitors (gliptins). If the glycohemoglobin A1c level drops by a percentage point (e.g from 9% to 8%) I will continue the new drug therapy. If the change is minor (less than a percentage point) then there is little reason to continue spending my patients’ money on a therapy which has failed. In these cases, insulin needs to be started. The nice thing about insulin treatment is that it almost always results in a swift and dramatic improvement in blood sugar. Few of my patients willingly accept insulin at the beginning and are glad they were given one more chance to stay on pill therapy, even if it is just a temporary reprieve.

These comments are for educational purposes only and do not constitute medical advice.

Gary Pepper
Editor in Chief, Metabolism.com

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