How does L-Carnitine work to help speed weight loss? What evidence is there that it works?

 

In a study of 18 overweight subjects, carnitine greatly increased weight loss. The subjects were split into two groups of 9. For 12 weeks, both groups ate a healthy diet and performed moderate exercise. One group was given 2000 mg of carnitine, and the other a placebo. In the placebo group, the average weight loss after 12 weeks was one pound. In the carnitine group, weight loss averaged 11 pounds. That’s an eleven-fold increase in weight loss, simply by increasing carnitine levels. Body fat percentage levels also decreased markedly in the carnitine group.

However, not everyone will experience such a dramatic effect of weight loss with carnitine. In a recent study, individuals taking carnitine for 8 weeks did not experience increased weight loss. So, how does one know if it is even worth trying this supplement. Well, in my experience, individuals following a reduced carbohydrate diet, and incorporating aerobics and strength training, usually find it easier to lose weight while taking carnitine on an empty stomach, 30 minutes before breakfast, when compared to those following the same protocol minus L-carnitine.

We hope all is well with you and that you find this information useful.

Articles of interest:

  • Rebouche CJ, Paulson DJ. Carnitine Metabolism and Function in Humans. Ann Rev Nutr 1986; 6:41-66.
  • Avogaro P, Bon GB, Cazzolato G, Rorai E. Acute Effects of L-carnitine on FFA and Beta-OH-Butyrate in Man. Pharmacol Res Commun 1981; 13 (5): 443-50.
  • Int J Sport Nutr Exerc Metab 2000 Jun;10(2):199-207

Good Luck!

Robert L. Pastore, Ph.D., CNC, CN
Senior Nutritionist at Metabolism.com

11 Responses to “How does L-Carnitine work to help speed weight loss? What evidence is there that it works?”

  1. Don on February 2nd, 2009 at 10:30 pm

    Could you please provide more details on this study? What institute carried it out? What year was conducted? Do you have a link to the full study?

  2. Dr. K.L. Planken on February 11th, 2009 at 5:44 am

    Interesting story about L-Carnitine. I looked up the references and I think you should also list the title of the third article: “L-Carnitine supplementation combined with aerobic training DOES NOT promote weight loss in moderately obese women”.

  3. amanda on September 24th, 2009 at 3:51 am

    Thanks for the tip, i lose 10 lbs in 7 days, followed the meal plan given by the Cosmo Body, im currently taking Cosmo Body L- Carnitine Supplement

  4. Matin on February 5th, 2010 at 10:58 am

    I started taking alli 3 days ago and today was the first time I noticed anything different happening with my body. First, I had to go to the bathroom really bad after my breakfast+alli and there were floating drops of fat. Then, I cannot stop passing really nasty smelling gas, and I’m continuously afraid to pass gas for fear I will pass something more. However, seeing the fat come out kind of makes me happy. Fat is good for you, but I don’t mind sending a bit of it down the shute. This experiment is pretty cool so far. And it does make me watch what I eat a little more.

  5. john on May 5th, 2010 at 1:02 am

    You are probably taken way in excess. I have never had any side effect.

  6. jason on May 18th, 2010 at 6:56 pm

    Matin, if you’re shitting or pissing fat then you should see a doctor. That is NOT a healthy result for any kind of supplement.

  7. Will on July 9th, 2010 at 12:25 pm

    If you really passed “fat” you are probably dying, or lying. I will guess the latter.

  8. Clinical Nutritionist on July 13th, 2010 at 5:39 pm

    I WOULD NOT RECOMMEND anything that CAUSES MALABSORPTION which can quickly lead to MALNUTRITION. This medication is designed to prevent absorption of nutrients (fat specifically in this case) but it also can interfere with fat soluble vitamin status. Drug induced nutrient depletions is a serious issue to be considered. Also, instead of trying to not absorb fat, the best thing to do is find out which fats are healthiest for us and eat them in moderation!

  9. angie on July 27th, 2010 at 7:31 pm

    Jason,

    About the Alli that Matin takes, fat if absorbed in your body and is then released by dumping. It’s orange and it stinks.

  10. GNLD International Distributors on August 7th, 2010 at 4:51 am

    It is a supplement that should only be taken if you are in perfect health due to its contraindications and, preferably even if you are in perfect health, only after seeking advice from your physician.

  11. sarah on August 13th, 2010 at 2:23 am

    it only has been a week of me taking godex, i lost 6 lbs no side effects so far. thank you for sharing your knowledge that i should take it 30 mins before meal. my doctor didnot instruct me about that

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