How does L-Carnitine work to help speed weight loss? What evidence is there that it works?

  Gary Pepper M.D.

In a study of 18 overweight subjects, carnitine greatly increased weight loss. The subjects were split into two groups of 9. For 12 weeks, both groups ate a healthy diet and performed moderate exercise. One group was given 2000 mg of carnitine, and the other a placebo. In the placebo group, the average weight loss after 12 weeks was one pound. In the carnitine group, weight loss averaged 11 pounds. That’s an eleven-fold increase in weight loss, simply by increasing carnitine levels. Body fat percentage levels also decreased markedly in the carnitine group.

However, not everyone will experience such a dramatic effect of weight loss with carnitine. In a recent study, individuals taking carnitine for 8 weeks did not experience increased weight loss. So, how does one know if it is even worth trying this supplement. Well, in my experience, individuals following a reduced carbohydrate diet, and incorporating aerobics and strength training, usually find it easier to lose weight while taking carnitine on an empty stomach, 30 minutes before breakfast, when compared to those following the same protocol minus L-carnitine.

We hope all is well with you and that you find this information useful.

Articles of interest:

  • Rebouche CJ, Paulson DJ. Carnitine Metabolism and Function in Humans. Ann Rev Nutr 1986; 6:41-66.
  • Avogaro P, Bon GB, Cazzolato G, Rorai E. Acute Effects of L-carnitine on FFA and Beta-OH-Butyrate in Man. Pharmacol Res Commun 1981; 13 (5): 443-50.
  • Int J Sport Nutr Exerc Metab 2000 Jun;10(2):199-207

Good Luck!

Robert L. Pastore, Ph.D., CNC, CN
Senior Nutritionist at Metabolism.com

4 Responses to “How does L-Carnitine work to help speed weight loss? What evidence is there that it works?”

  1. Don on February 2nd, 2009 at 10:30 pm

    Could you please provide more details on this study? What institute carried it out? What year was conducted? Do you have a link to the full study?

  2. Dr. K.L. Planken on February 11th, 2009 at 5:44 am

    Interesting story about L-Carnitine. I looked up the references and I think you should also list the title of the third article: “L-Carnitine supplementation combined with aerobic training DOES NOT promote weight loss in moderately obese women”.

  3. amanda on September 24th, 2009 at 3:51 am

    Thanks for the tip, i lose 10 lbs in 7 days, followed the meal plan given by the Cosmo Body, im currently taking Cosmo Body L- Carnitine Supplement

  4. Matin on February 5th, 2010 at 10:58 am

    I started taking alli 3 days ago and today was the first time I noticed anything different happening with my body. First, I had to go to the bathroom really bad after my breakfast+alli and there were floating drops of fat. Then, I cannot stop passing really nasty smelling gas, and I’m continuously afraid to pass gas for fear I will pass something more. However, seeing the fat come out kind of makes me happy. Fat is good for you, but I don’t mind sending a bit of it down the shute. This experiment is pretty cool so far. And it does make me watch what I eat a little more.

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This entry was posted on Saturday, August 23rd, 2008 and is filed under general health & nutrition. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.
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